Managing Side Effects on GLP-1 Weight Loss Medication

What Side Effects Are Common on GLP-1's?

Many people experience some side effects when starting or adjusting their dose:

  • Nausea or upset stomach
  • Feeling cold
  • Constipation or digestive changes
  • Fatigue or low energy
  • Headaches or dizziness

These often improve after a few weeks but can be a barrier if not managed well.

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How to Manage Nausea and Digestive Upset

  • Eat small, frequent meals instead of big ones
  • Choose bland, easy-to-digest foods like bananas, rice, toast, and apple sauce when nausea strikes
  • Avoid fatty, fried, or spicy foods early on
  • Stay well-hydrated — sip water or herbal tea throughout the day
  • Ginger tea or ginger soda may help settle your stomach

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Constipation? Here’s What Works

  • Increase fibre intake gradually through vegetables, chia/flax seeds, or psyllium husk
  • Drink plenty of water (at least 2L daily)
  • Move your body with daily gentle exercise like walking or stretching
  • Consider a mild stool softener only if needed and after consulting your healthcare provider

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Boosting Energy and Reducing Fatigue

  • Focus on protein-rich meals and snacks to stabilize blood sugar and support muscles
  • Ensure you’re getting enough vitamins and minerals — fatigue is often a sign of deficiencies
  • Prioritize quality sleep: wind down 30 minutes before bed, avoid screens, and keep your room cool and dark
  • Stay hydrated and avoid caffeine late in the day

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When to Talk to Your Healthcare Provider

If side effects:

  • Don’t improve after a few weeks
  • Are severe or worsening
  • Cause you to stop your medication

Then please consult your doctor or pharmacist promptly.

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Bottom Line

Side effects can be managed and usually improve. With small changes to meals, hydration, and lifestyle, you can keep your Mounjaro journey comfortable and effective.